Anabolic steroid for systemic use - depot form
Active substance
Nandrolone decanoate (nandrolone)
Release form, composition and packaging
Oily solution for intramuscular injection greenish-yellow in color, transparent, with a characteristic odor, free from mechanical inclusions.
Excipients: benzyl alcohol, isopropanol, sunflower oil (for injection).
1 ml - colorless glass ampoules (1) - plastic trays (1) - cardboard packs.
pharmachologic effect
Retabolil is a synthetic testosterone derivative, a long-acting anabolic drug (depot drug). Stimulates protein synthesis in the body, causes retention of nitrogen, calcium, sodium, potassium, chlorides and phosphorus, which leads to an increase in muscle mass and accelerated bone growth, water retention in the body. Has low androgenic activity.
Pharmacokinetics
Suction and distribution
Nandrolone decanoate is slowly released from the injection site into the bloodstream with a half-life of 6 days. In the blood, the ester is quickly hydrolyzed into nandrolone with a half-life of less than 1 hour. In general, T1/2 for the combined process of hydrolysis, distribution and excretion of nandrolone is 4.3 hours.
Metabolism and excretion
Nandrolone is metabolized in the liver. Metabolites excreted by the kidneys are 19-norandosterone, 19-noretiocholanone and 19-norepantrosterone. Data on the pharmacological activity of these metabolites are not known.
Indications
— osteoporosis of various origins;
— cachexia of various etiologies;
— disruption of protein metabolism, increased catabolic processes that deplete the body’s resources (burns, injuries, surgeries, radiation therapy, severe infectious diseases);
- progressive muscular dystrophy;
— amyotrophy spinal progressive Werdnig-Hoffman;
- glomerulonephritis;
— program hemodialysis in patients with chronic renal failure.
Contraindications
- hypersensitivity to any of the components of the drug;
- pregnancy;
- lactation;
- nephrotic syndrome;
- prostate cancer;
- spicy or chronic prostatitis;
- breast cancer in men;
- severe liver damage, liver failure in cancer patients or liver metastases;
- breast cancer (with metastases in the presence of hypercalcemia);
- hypercalcemia (including history).
Carefully:, liver and kidney failure, arterial hypertension, severe atherosclerosis, myocardial infarction (including a history), cerebrovascular accident, diabetes mellitus, prostate hypertrophy, migraine, epilepsy, history of glaucoma (anabolic steroids cause sodium and fluid retention in organism), elderly age, convulsions (including a history).
Due to androgenic activity, the drug is prescribed to women and children if the expected effect of therapy exceeds the possible risk.
Dosage
The drug is administered deep intramuscularly.
The dose of the drug is determined individually.
Average single dose for adults is 25-50 mg every 3-4 weeks.
At severe renal failure, incl. With uremia, the dose is 50 mg weekly.
For children Retabolil is prescribed at a dose of 400 mcg/kg body weight every 3-4 weeks.
Side effects
When using the drug Retabolil according to the recommended dosage regimen, the occurrence of adverse reactions is usually unlikely. With prolonged use or in case of abuse of the drug, the following may appear: adverse reactions.
In patients of both sexes
From the outside digestive system: nausea, vomiting, loss of appetite, burning sensation in the tongue, impaired liver function with jaundice, hepatonecrosis (dark stool, vomiting with blood, headache, feeling of discomfort, unpleasant liver odor from the mouth), hepatocellular carcinoma, peliosis of the liver (loss of appetite, dark urine, discoloration of stool, urticaria, pinpoint or macular hemorrhagic rashes on the skin and mucous membranes of the mouth and nose), cholestatic hepatitis (yellow discoloration of the sclera and skin, pain in the right hypochondrium, dark urine, discoloration of stool), diarrhea, feeling of fullness in the stomach, flatulence,
From the reproductive system: increased or decreased libido,
From the skin: acne (especially in women and pubescent boys), increased vascularization of the skin.
From the side of metabolism: retention of nitrogen, sodium and water in the body, peripheral edema, hypercalcemia (especially in immobile patients and in women with metastases of breast cancer). Progression of atherosclerosis (increased concentration of low-density lipoproteins - LDL and decreased concentration of high-density lipoproteins - HDL), Iron-deficiency anemia, leukemoid syndrome (leukemia, pain in long bones, hypocoagulation with a tendency to bleeding), increased secretion of the sebaceous glands, chills, convulsions, sleep disturbance.
suppression of the secretion of gonadotropic hormones.
Among women
From the endocrine system: symptoms of virilization (hirsutism, alopecia, irreversible decrease in voice tone, dys- and amenorrhea, suppression of ovarian function, clitoral enlargement, steroid acne, oily skin).
Metabolism: hypercalcemia (nausea, vomiting, increased fatigue).
In men
From the endocrine system: in the prepubertal period - virilism (acne, penis enlargement, priapism, formation of secondary sexual characteristics), idiopathic hyperpigmentation of the skin, slowing or cessation of growth (calcification of the epiphyseal growth zones of tubular bones); in the postpubertal period - bladder irritation (increased frequency of urges), mastodynia, gynecomastia, priapism, oligospermia, decreased sexual function.
From the reproductive system: in elderly patients - prostate hyperplasia and/or carcinoma.
Overdose
There is no data on overdose.
Symptoms: strengthening the above side effects.
Treatment: carrying out symptomatic therapy. There is no specific antidote.
Drug interactions
Retabolil should be prescribed with caution when using antiplatelet agents and indirect action(their effect may be enhanced), hypoglycemic drugs (their hypoglycemic effect may be enhanced).
Retabolil can be used as part of combination therapy with corticosteroids, tuberculostatic and cytostatic drugs.
Weakens the effects of growth hormone and its derivatives (accelerates the mineralization of the epiphyseal growth zones of tubular bones).
Glucocorticoids and mineralocorticoids, corticotropin, sodium-containing drugs and foods rich in sodium increase (mutually) fluid retention in the body, increase the risk of developing edema, and increase the severity of acne.
Concomitant administration with hepatotoxic drugs medicines increases the risk of liver dysfunction.
special instructions
To achieve an optimal therapeutic effect during therapy with Retabolil, the patient must receive an adequate amount of proteins, fats, carbohydrates, and minerals from food.
When using the drug Retabolil in high doses during puberty, premature closure of growth plates and growth arrest are possible. Acceleration of epiphyseal growth of tubular bones can be observed in children both during treatment and 6 months after stopping the drug.
To monitor the condition of the epiphyseal growth zones of tubular bones in children and adolescents, it is recommended to have them X-rayed every 6 months.
During treatment with Retabolil, intraocular pressure should be carefully monitored.
During treatment, systematic monitoring of the blood concentration of calcium ions, cholesterol (especially in patients with concomitant pathology of the cardiovascular system), hematocrit, hemoglobin, and serum phosphorus concentration is necessary.
In some cases, during the use of the drug, disturbances in the performance of some functional liver tests are observed. Therefore, liver function should be monitored every 4 weeks.
In patients diabetes mellitus Retabolil may cause an increase in tolerance to, thereby reducing the need for insulin or oral hypoglycemic agents.
If menstrual irregularities occur and/or signs of virilization appear, treatment should be discontinued.
Use strictly as prescribed by your doctor to avoid complications.
Before starting and during treatment with the drug, it is necessary to perform rectal monitoring of the size of the prostate gland.
Abuse of drugs containing nandrolone (when used in high doses as an anabolic agent) can cause endocrine, metabolic and mental disorders.
The use of anabolic steroids for the purpose of stimulating athletic performance can cause serious harm to health and is unacceptable!
The Retabolil solution may become cloudy under the influence of cold. In this case, before use, the ampoule with the drug must be heated until the crystals dissolve.
Impact on the ability to drive vehicles and machinery
Does not affect the ability to drive vehicles and perform work associated with a high risk of injury.
Release form, composition and packaging
Oily solution for intramuscular injection greenish-yellow in color, transparent, with a characteristic odor, without foreign visible mechanical inclusions.
Excipients: benzyl alcohol, isopropyl alcohol, sunflower oil.
1 ml - ampoules (1) - cardboard packs.
Clinical and pharmacological group: Anabolic steroid for systemic use - depot form
Registration number: P N014823/01
Registration date: 26.12.08
Packaging Details: solution for intramuscular injection, oil 50 mg/1 ml: amp. 1 PC.
The description of the drug RETABOLIL is based on the officially approved instructions for use of the drug RETABOLIL for specialists and approved by the manufacturer for the 2013 edition.
pharmachologic effect
Retabolil is a synthetic testosterone derivative, a long-acting anabolic drug (depot drug). Stimulates protein synthesis in the body, causes retention of nitrogen, calcium, sodium, potassium, chlorides and phosphorus, which leads to an increase in muscle mass and accelerated bone growth, water retention in the body. Has low androgenic activity.
Pharmacokinetics
Nandrolone decanoate is slowly released from the injection site into the bloodstream with a half-life of 6 days. In the blood, the ester is quickly hydrolyzed into nandrolone with a half-life of less than 1 hour. In general, T1/2 for the combined process of hydrolysis, distribution and removal of nandrolone from plasma is 4.3 hours. Nandrolone is metabolized in the liver. Metabolites excreted by the kidneys are 19-norandosterone, 19-noretiocholanone and 19-norepantrosterone. Data on the pharmacological activity of these metabolites are not known.
Indications
Use strictly as prescribed by your doctor to avoid complications.
Diseases that require long-term use of anabolic drugs:
— osteoporosis of various origins;
— cachexia of various etiologies;
— disturbance of protein metabolism after serious burns, injuries, surgeries, radiation therapy, and severe infectious diseases;
- progressive muscular dystrophy;
— spinal amyotrophy of Werdnig-Hoffmann;
- diabetic retinopathy;
— disseminated breast cancer in women (as a palliative treatment);
- glomerulonephritis, program hemodialysis in patients with chronic renal failure.
Retabolil can be used in combination therapy with glucocorticoids, tuberculostatic and cytostatic drugs.
Dosage regimen
Retabolil can be prescribed to both inpatient and outpatient patients. The drug is administered deep intramuscularly. The dose of the drug is determined individually. The average single dose for adults is 25-50 mg every 3-4 weeks. For myopathies, individual doses can be set. For severe renal failure, the dose is 50 mg weekly. Cancer patients can be prescribed a dose of 50 mg every 5 days.
For children, Retabolil is prescribed at a dose of 400 mcg/kg body weight every 3-4 weeks.
Side effect
In patients of both sexes: nausea, loss of appetite, vomiting, burning sensation in the tongue, increased or decreased libido, acne (especially in women and puberty boys). There may be retention of nitrogen, sodium and water in the body, edema, cholestasis, jaundice, increased vascularization of the skin, hypercalcemia (especially in immobile patients and in women with metastases of breast cancer).
Suppression of gonadotropin secretion.
In women: symptoms of virilization (hirsutism, baldness, irreversible decrease in voice tone, menstrual irregularities, suppression of ovarian function, enlarged clitoris).
In men: suppression of testicular function, oligospermia, gynecomastia, penile enlargement, frequent erections during puberty.
Contraindications
- nephrotic syndrome;
- prostate cancer;
— acute or chronic prostatitis;
- breast cancer in men;
- severe liver damage, liver failure in cancer patients or liver metastases;
- pregnancy and breastfeeding;
- hypersensitivity to any of the components of the drug.
Use of the drug RETABOLIL during pregnancy and breastfeeding
The drug is contraindicated for use during pregnancy and breastfeeding.
Use of the drug RETABOLIL for liver dysfunction
The drug is contraindicated for use in severe liver damage, liver failure in cancer patients or in patients with liver metastases.
Use of the drug RETABOLIL for renal impairment
The drug is prescribed with caution to patients with renal failure.
Use of the drug RETABOLIL in elderly patients
Data on the use of Retabolil in elderly patients are not provided.
Use of the drug RETABOLIL in children
Due to androgenic activity, the drug is prescribed to children if the expected benefit outweighs the potential risk. When Retabolil is used in high doses during puberty, premature closure of growth plates and growth arrest are possible.
special instructions
To achieve an optimal therapeutic effect during therapy with Retabolil, the patient must receive an adequate amount of proteins, fats, carbohydrates, vitamins, and minerals from food.
Due to androgenic activity, the drug is prescribed to women and children if the expected benefit outweighs the potential risk.
When Retabolil is used in high doses during puberty, premature closure of growth plates and growth arrest are possible.
The drug should be used with caution in case of heart failure, renal failure, arterial hypertension, migraine, epilepsy, glaucoma (or if there is a history of them), since anabolic steroids cause sodium and fluid retention in the body. During treatment with Retabolil, intraocular pressure should be carefully monitored.
Before starting and during treatment with the drug, it is necessary to perform rectal monitoring of the size of the prostate gland.
In some cases, during the use of the drug, disturbances in the performance of some functional liver tests are observed. Therefore, liver function should be monitored every 4 weeks.
In patients with diabetes, Retabolil may cause an increase in glucose tolerance, thereby reducing the need for insulin or oral hypoglycemic agents.
Patients with breast cancer metastases to bone may develop hypercalcemia. In this case, anabolic steroid therapy can be prescribed only after normalization of calcium levels in the blood.
The use of anabolic steroids for the purpose of stimulating athletic performance can cause serious harm to health and is unacceptable!
Overdose
Symptoms: increased described side effects.
Symptomatic therapy is carried out. There is no specific antidote. If signs of virilization appear, discontinuation of the drug is indicated.
Drug interactions
Retabolil should be prescribed with caution when using indirect anticoagulants (their effect may be enhanced), hypoglycemic drugs (their hypoglycemic effect may be enhanced).
Conditions for dispensing from pharmacies
The drug is available with a prescription.
Storage conditions and expiration dates
Storage conditions:
Store at a temperature of 15-30°C, out of the reach of children.
The Retabolil solution may become cloudy under the influence of cold. In this case, before use, the ampoule with the drug must be heated until the crystals dissolve.
Best before date:
Do not use the drug after the expiration date indicated on the package.
, isopropyl And benzyl alcohol , purified sunflower oil.
Release form
The medicine is released in the form of a solution for intramuscular injection in ampoules of one milliliter, one ampoule in a cardboard box.
The drug is a yellow-green oily liquid, has a specific characteristic odor, and is homogeneous.
pharmachologic effect
Anabolic.
Pharmacodynamics and pharmacokinetics
On Wikipedia nandrolone - This anabolic steroid , having an extended effect. The androgenic effect of the substance is weakly expressed. Nandrolone – a derivative whose anabolic effect is more pronounced.
The drug stimulates erythropoiesis , the amount in the body increases, the level increases, and the speed and intensity of protein synthesis increases. It is noteworthy that the product does not contain C17-alpha-alkyl group that can cause liver problems and affect the development cholestasis .
Anabolic And androgenic the indices in the product are successfully combined, so the drug is often used in bodybuilding to gain muscle mass. It does not cause problems with spermatogenesis and skin rashes, low toxicity to the liver.
Retabolil smoothly released from the injection site and enters the bloodstream. The half-life from the body is 6 days. the drug undergoes in the liver. Basic – 19-norandrosterone , 19-norepiandrosterone And 19-noretiocholonolone are excreted in the urine. The therapeutic effect occurs on the 3rd day after taking the first dose.
Indications for use
The drug is prescribed:
- with progressive muscular dystrophy ;
- with different origins;
- to restore normal protein metabolism after burns , injuries , radiation therapy , severe infections and operations;
- at cachexia ;
- for treatment disseminated among women;
- at Werdnig-Hoffmann spinal amyotrophy ;
- at ;
- for gaining muscle mass (in bodybuilding);
- at .
The medicine can be combined with cytostatics , glucocorticosteroids , tuberculostatics .
Contraindications
Retabolil is contraindicated:
- at and during ;
- children under 18 years of age;
- at prostate carcinoma and mammary glands in men;
- after the occurrence nephrotic syndrome after prolonged therapy anabolic steroids ;
- at y cancer patients ;
- if the patient has the components of the drug;
- at porphyria ;
- for severe liver diseases.
Side effects
If the drug is taken as recommended in recommended therapeutic doses, adverse reactions are rare.
With long-term use, the following may occur:
- reactions hypersensitivity ;
- nausea, burning sensation on the tongue, vomiting;
- disturbances in the functioning of the ovaries (hypo- or hyperfunction);
- , skin rashes ;
- jaundice , liver diseases;
- retention of water, sodium, nitrogen and ;
- decreased secretion level.
With insufficient physical activity and in women with breast cancer, it may develop hypercalcemia .
Men sometimes develop oligospermia , penis increases and frequency erections , the mammary glands become inflamed.
Instructions for use of Retabolil (Method and dosage)
The drug is prescribed to both inpatient and outpatient patients.
The medicine is administered intramuscularly, deeply.
The dosage is determined by the attending physician, depending on the disease. As a rule, adults are prescribed 25 to 50 mg of the drug once a month. The dosage for children (in case of urgent need, if the drug was prescribed by a doctor) is calculated at 400 mcg per kg of child weight, the frequency of administration is the same as for adults.
Instructions for Retabolil for anemia
Men are prescribed 200 mg once a week, women – 100 mg once every 7 days. If six months have passed since the start of treatment with the drug, and there has been no improvement, the drug should be discontinued.
Constant monitoring of blood counts and the body’s tolerance level to glucose .
Terms of sale
In order to purchase medicine at a pharmacy, you will need a prescription in Latin, written by your doctor.
Storage conditions
The drug should be stored in its original packaging, in a dark and cool place (temperature no higher than 25 degrees).
If sediment has formed at the bottom of the ampoule, but the expiration date has not yet expired, it should be heated until the sediment dissolves. Only a clear solution can be administered intramuscularly.
Keep away from children.
Best before date
special instructions
If the drug is prescribed to women, then it is necessary to carefully evaluate the balance of benefit and harm from the drug, due to its androgenic effects on the body.
Persons under 18 years of age may develop hypercalcemia And hypercalciuria .
Synonyms
Superbolan, Abolon, Decanabol, Fortabolin, Nandrolone decanoate, Anabozan-Depot, Decanandroline, Eubolin, Hormoretard, Superbolan, Northestosterone decanoate, Turinabol-Depot.
During pregnancy and lactation
Use of the product during pregnancy and lactation is prohibited.
P N014823/01Tradename: Retabolil
International nonproprietary name:
NandroloneDosage form:
solution for intramuscular administration (oil)Compound:
1 ml of oil solution for injection contains:Active substance– nandrolone decanoate 50.00 mg
Excipients– benzyl alcohol, isopropanol, sunflower oil (for injection).
Description
Greenish-yellow transparent oil solution with a characteristic odor, free from mechanical inclusions.
Pharmacotherapeutic group:
anabolic steroid drug.ATX code: A14A B01
Pharmacological properties
Pharmacodynamics: Retabolil is a synthetic testosterone derivative, a long-acting anabolic drug (depot drug). Stimulates protein synthesis in the body, causes retention of nitrogen, calcium, sodium, potassium, chlorides and phosphorus, which leads to an increase in muscle mass and accelerated bone growth, water retention in the body. Has low androgenic activity.
Pharmacokinetics. Nandrolone decanoate is slowly released from the injection site into the bloodstream with a half-life of 6 days. In the blood, the ester is rapidly hydrolyzed into nandrolone with a half-life of less than 1 hour. In general, the half-life for the combined process of hydrolysis, distribution and elimination of nandrolone from plasma is 4.3 hours. Nandrolone is metabolized in the liver. Metabolites excreted by the kidneys are 19-norandrosterone, 19-noretiocholanone and 19-norepiandrosterone. Data on the pharmacological activity of these metabolites are unknown.
Indications for use
Due to androgenic activity, the drug is prescribed to women and children if the expected effect of therapy exceeds the possible risk. Directions for use and doses
The drug is administered deeply intramuscularly. The dose of the drug is determined individually. The average single dose for adults is 25-50 mg every 3-4 weeks. For severe renal failure, including uremia, the dose is 50 mg weekly.
For children, Retabolil is prescribed at a dose of 400 mcg/kg body weight every 3-4 weeks. Side effect
When using the drug Retabolil according to the recommended dosage regimen, side effects are usually unlikely. With long-term use or in case of abuse of the drug, the following side effects may occur:
In patients of both sexes: nausea, vomiting, loss of appetite, abdominal pain, burning sensation in the tongue, impaired liver function with jaundice, hepatonecrosis (dark stool, vomiting with blood, headache, discomfort, bad liver odor), hepatocellular carcinoma, peliosis of the liver (loss of appetite, dark urine, discoloration of stool, urticaria, pinpoint or macular hemorrhagic rashes on the skin and mucous membranes of the mouth and nose), cholestatic hepatitis (yellow discoloration of the sclera and skin, pain in the right hypochondrium, dark urine, discoloration of stool), diarrhea , feeling of fullness in the stomach, flatulence, increased or decreased libido, acne (especially in women and puberty boys).
Retention of nitrogen, sodium and water in the body, peripheral edema, increased vascularization of the skin, hypercalcemia (especially in immobile patients and women with metastases of breast cancer) may be observed.
Progression of atherosclerosis (increased concentration of low-density lipoproteins - LDL and decreased concentration of high-density lipoproteins - HDL), iron deficiency anemia, leukemoid syndrome (leukemia, pain in long bones, hypocoagulation with a tendency to bleeding), increased secretion of the sebaceous glands, chills, convulsions, sleep disturbance.
Suppression of the secretion of gonadotropic hormones.
In women: symptoms of virilization (hirsutism, alopecia, irreversible decrease in voice, dys- and amenorrhea, suppression of ovarian function, clitoral enlargement, steroid acne, oily skin), hypercalcemia (nausea, vomiting, fatigue).
In men: in the prepubertal period - virilism (acne, penis enlargement, priapism, formation of secondary sexual characteristics), idnopathic hyperpigmentation of the skin, slowdown or cessation of growth (calcification of the epiphyseal growth zones of tubular bones); in the postpubertal period - irritation of the bladder (increased frequency of urges), mastodynia, gynecomastia, priapism, oligospermia, decreased sexual function; elderly – prostate hyperplasia and/or carcinoma. Overdose
There is no data on overdose.
Symptoms: increased side effects described above.
Treatment: symptomatic. There is no specific antidote. Interaction with other drugs
Retabolil should be prescribed with caution when using antiplatelet agents and indirect anticoagulants (their effect may be enhanced), hypoglycemic drugs (their hypoglycemic effect may be enhanced).
Retabolil can be used in combination therapy with glucocorticosteroids, tuberculostatic and cytostatic drugs.
Weakens the effects of somatotropic hormone and its derivatives (accelerates the mineralization of the epiphyseal growth zones of tubular bones). Glucocorticosteroids and mineralocorticoids, corticotropin, sodium-containing medications and foods rich in sodium increase (mutually) fluid retention in the body, increase the risk of developing edema, and increase the severity of acne.
Concomitant administration with hepatotoxic drugs increases the risk of liver dysfunction. special instructions
To achieve an optimal therapeutic effect during therapy with Retabolil, the patient must receive an adequate amount of proteins, fats, carbohydrates, vitamins, and minerals.
When Retabolil is used in high doses during puberty, premature closure of growth plates and growth arrest are possible. Acceleration of epiphyseal growth of tubular bones can be observed in children both during treatment and 6 months after stopping the drug.
To monitor the condition of the epiphyseal growth zones of tubular bones in children and adolescents, it is recommended that they be examined by X-ray every 6 months.
During treatment with Retabolil, intraocular pressure should be carefully monitored.
During treatment, systematic monitoring of the blood concentration of calcium ions, cholesterol (especially in patients with concomitant pathology of the cardiovascular system), hematocrit, hemoglobin, and serum phosphorus concentration is necessary.
In some cases, during the use of the drug, disturbances in the performance of some functional liver tests are observed. Therefore, liver function should be monitored every 4 weeks.
In patients with diabetes mellitus, Retabolil may cause an increase in glucose tolerance, thereby reducing the need for insulin or oral hypoglycemic agents.
If menstrual irregularities occur and/or signs of virilization appear, treatment should be discontinued.
Use strictly as prescribed by your doctor to avoid complications.
Before starting and during treatment with the drug, it is necessary to perform rectal monitoring of the size of the prostate gland.
Abuse of drugs containing nandrolone (when used in high doses as an anabolic agent) can cause endocrine, metabolic and mental disorders.
The use of anabolic steroids for the purpose of stimulating athletic performance can cause serious harm to health and is unacceptable!
The Retabolil solution may become cloudy under the influence of cold. In this case, before use, the ampoule with the drug must be heated until the crystals dissolve. Effect of the drug on the ability to drive vehicles and machinery: does not affect the ability to drive vehicles and perform work associated with a high risk of injury. Release form
Solution for intramuscular administration (oil) 50 mg/ml.
1 ml of solution for intramuscular administration (oil) containing 50 mg of nandrolone decanoate, in a colorless glass ampoule of hydrolytic class 1 with a blue break point. 1 ampoule in a plastic tray. 1 plastic pallet along with instructions for use in a cardboard box.? Storage conditions
List B. At a temperature of 15-25 ° C, in a place protected from light.
Keep out of the reach of children! Best before date
5 years.
Do not use after the expiration date stated on the package. Conditions for dispensing from pharmacies
On prescription. Name and address of the manufacturer JSC Gedeon Richter
1103 Budapest, st. Demrei, 19-21, Hungary. Consumer complaints should be sent to:
Moscow Representative Office of JSC Gedeon Richter
119049, 4th Dobryninsky lane, no.8.
|
Retabolil Analogs
(generics, synonyms)
Nandrolone decanoate
Recipe (international)
Rp.: Sol. Retabolili ol. 5% pro injection 1 ml
D.t.d. No. 4
pharmachologic effect
S. i.m. I p/3 weeks
Long-acting anabolic steroid. Stimulates protein synthesis in the body, promotes retention of nitrogen, phosphorus, sulfur, and potassium in the body. Promotes fixation of calcium in bones, increasing bone mass in osteoporosis. Causes an increase in appetite, an increase in muscle mass with a corresponding increase in body weight. In women with disseminated breast carcinoma, it helps to improve the condition over many months. Characterized by long-lasting action.
Mode of application For adults:
Used at a dose of 50 mg intramuscularly once every 3 weeks.
Indications
In cases of protein metabolism disorders, it is possible to use a smaller dose - 25 mg IM once every 3 weeks.
Cachexia of various etiologies;
- asthenia;
- the need to accelerate regeneration (including in case of fractures, injuries);
- disturbances of protein metabolism after severe injuries, operations, burns, radiation therapy, and infectious diseases accompanied by protein loss;
- for diabetic retinopathy, nephropathy;
- stimulation of growth in children with growth retardation;
- the need for long-term anabolic therapy for progressive muscular dystrophy, osteoporosis and cancer;
- disseminated breast cancer in women.
Contraindications
Prostate cancer
- acute and chronic prostatitis
- breast cancer in men
- hepatitis
- acute liver dystrophy
- pregnancy, lactation.
Side effects
Side effects are most likely when using nandrolone in high doses.
- From the endocrine system: virilization in girls, women (deepening of the voice, male-type hair growth) and boys in the prepubertal period; amenorrhea, impaired spermatogenesis.
- Metabolism: possible premature ossification of the epiphyses and growth retardation; fluid retention in the body.
Release form
Solution for injection. oily 50 mg/1 ml: amp. 1 PC.
Oil injection solution 1 ml
nandrolone decanoate 50 mg
Excipients: benzyl alcohol, isopropyl alcohol.
1 ml - ampoules (1) - cardboard packs.
ATTENTION!
The information on the page you are viewing is created for informational purposes only and does not in any way promote self-medication. The resource is intended to provide healthcare workers with additional information about certain medications, thereby increasing their level of professionalism. The use of the drug "" necessarily requires consultation with a specialist, as well as his recommendations on the method of use and dosage of the medicine you have chosen.